My research investigates the pathologies arising from metabolic disturbances, particularly those induced by high-fat, high-sugar, or high-sodium diets. These dietary patterns can lead to hypertension, hyperlipidemia, hyperglycemia, insulin resistance, and calcium dysregulation, ultimately contributing to osteoporosis.

Furthermore, I explore the therapeutic potential of anti-diabetic drugs and herbal extracts in mitigating these metabolic disturbances and restoring calcium homeostasis, thereby improving bone health.

In addition to these studies, I also investigate the effects of mechanical loading on osteoblast and osteoclast function, employing mechanosensitive ion channel mimetics under simulated microgravity conditions.

These studies encompass a range of experimental models, from cell cultures and organ baths to in vivo animal studies. We utilize diverse techniques, including high-resolution microCT, synchrotron-based X-ray analyses (FT-IR, XTM, SAXS), multi-omics approaches (transcriptomics, proteomics, metabolomics), confocal microscopy, clinostats, and organ baths, among others.