Analytical performance of centrifuge-based device for clinical chemistry testing

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Abstract

Background: A centrifuge-based device has been introduced to the Samsung Blood Analyzer (SBA). The verification of this analyzer is essential to meet the ISO15189 standard. Methods: Analytical performance was evaluated according to the NCCLS EP05-A method. The results of plasma samples were compared between the SBA and a Hitachi 917 analyzer according to the NCCLS EP09-A2-IR method. Percent recovery was determined via analysis of original control serum and spiked serum. Results: Within-run precision was found to be 0.00-6.61% and 0.96-5.99% in normal- and abnormal-level assays, respectively, while between-run precision was 1.31-9.09% and 0.89-6.92%, respectively. The correlation coefficients (r) were > 0.990. The SBA presented analytical accuracy at 96.64 ± 3.39% to 102.82 ± 2.75% and 98.31 ± 4.04% to 103.61 ± 8.28% recovery, respectively. Conclusions: The results obtained verify that all of the 13 tests performed using the SBA demonstrates good and reliable precision suitable for use in qualified clinical chemistry laboratory service.

Original languageEnglish
Pages (from-to)1313-1318
Number of pages6
JournalClinical Laboratory
Volume58
Issue number11-12
Publication statusPublished - 2012

Keywords

  • Analytical performance
  • Blood analyzer
  • Clinical chemistry

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