Antibacterial Effect of Experimental Orthodontic Adhesives Containing Gold Nanoparticles Against Streptococcus mutans and Streptococcus sobrinus

Pinyada Akarajarasrod, Surachai Dechkunakorn, Pornpen Tantivitayakul, Primana Punnakitikashem, Wassana Wichai, Phetladda Pannak Whitis, Niwat Anuwongnukroh

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)

Abstract

Enamel decalcification usually can be found around orthodontic bracket after debonding. Orthodontic adhesives resistant to bacterial colonization were used to prevent white spot lesion and dental caries in orthodontic treatment with fixed appliance. The objectives of this study were to evaluate the antibacterial properties of expeimental orthodontic adhesive containing gold nanoparticles (AuNPs). 108 orthodontic adhesive discs containing 1.0 wt%, 0.5 wt%, 0.25 wt% AuNPs and without AuNPs were prepared from in-house orthodontic adhesive (27 discs per group). The antibcterial properties of adhesive discs were evaluated by direct contact test. Streptococcus mutans and Streptococcus sobrinus suspensions were placed on the discs and incubated at 37 °C for 1 hour. The adhesive discs were transferred to BHI broth and were incubated at 37◦C for 16, 20 and 24 h. Bacterial growth was evaluated by optical density (OD) measurement at 590nm. The results showed that experimental orthodontic adhesives with 1.0 wt% and 0.5 wt% AuNPs exhibited higher antibacterial activity compared to the control group (p < 0.05). At 24 h of incubation, the median OD of 1.0 wt%, 0.5 wt%, 0.25 wt% and control in S. mutans were 0.109, 0.006, 0.007 and 0.372, rescpectively. In S. sobrinus, the median OD were 0.173, 0.012, 0.007 and 0.328. The incorporation of gold nanoparticles into orthodontic adhesives exhibited antibacterial activity against cariogenic microorganism. At a concentration of 0.5 wt% and 1.0 wt% AuNPs, experimental orthodontic adhesive could reduce bacterial growth of both S. mutans and S. sobrinus.

Original languageEnglish
Title of host publicationAdvanced Materials and Engineering Materials X - Selected peer-reviewed full text papers from the 10th ICAMEM and 7th ICMSSM, 2021
EditorsPeng Sheng Wei, Yan Zhang Xi
PublisherTrans Tech Publications Ltd
Pages301-308
Number of pages8
ISBN (Print)9783035718775
DOIs
Publication statusPublished - 2021
Event10th International Conference on Advanced Materials and Engineering Materials, ICAMEM 2021 and 7th International Conference on Mechanical Structures and Smart Materials, ICMSSM 2021 - Virtual, Online
Duration: 14 Jun 202115 Jun 2021

Publication series

NameKey Engineering Materials
Volume904 KEM
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

Conference10th International Conference on Advanced Materials and Engineering Materials, ICAMEM 2021 and 7th International Conference on Mechanical Structures and Smart Materials, ICMSSM 2021
CityVirtual, Online
Period14/06/2115/06/21

Keywords

  • Antibacterial effect
  • Gold nanoparticles
  • Orthodontic adhesives
  • Streptococcus mutans
  • Streptococcus sobrinus

Fingerprint

Dive into the research topics of 'Antibacterial Effect of Experimental Orthodontic Adhesives Containing Gold Nanoparticles Against Streptococcus mutans and Streptococcus sobrinus'. Together they form a unique fingerprint.

Cite this