TY - GEN
T1 - Antibacterial Effect of Experimental Orthodontic Adhesives Containing Gold Nanoparticles Against Streptococcus mutans and Streptococcus sobrinus
AU - Akarajarasrod, Pinyada
AU - Dechkunakorn, Surachai
AU - Tantivitayakul, Pornpen
AU - Punnakitikashem, Primana
AU - Wichai, Wassana
AU - Whitis, Phetladda Pannak
AU - Anuwongnukroh, Niwat
N1 - Publisher Copyright:
© 2021 Trans Tech Publications Ltd, Switzerland.
PY - 2021
Y1 - 2021
N2 - Enamel decalcification usually can be found around orthodontic bracket after debonding. Orthodontic adhesives resistant to bacterial colonization were used to prevent white spot lesion and dental caries in orthodontic treatment with fixed appliance. The objectives of this study were to evaluate the antibacterial properties of expeimental orthodontic adhesive containing gold nanoparticles (AuNPs). 108 orthodontic adhesive discs containing 1.0 wt%, 0.5 wt%, 0.25 wt% AuNPs and without AuNPs were prepared from in-house orthodontic adhesive (27 discs per group). The antibcterial properties of adhesive discs were evaluated by direct contact test. Streptococcus mutans and Streptococcus sobrinus suspensions were placed on the discs and incubated at 37 °C for 1 hour. The adhesive discs were transferred to BHI broth and were incubated at 37◦C for 16, 20 and 24 h. Bacterial growth was evaluated by optical density (OD) measurement at 590nm. The results showed that experimental orthodontic adhesives with 1.0 wt% and 0.5 wt% AuNPs exhibited higher antibacterial activity compared to the control group (p < 0.05). At 24 h of incubation, the median OD of 1.0 wt%, 0.5 wt%, 0.25 wt% and control in S. mutans were 0.109, 0.006, 0.007 and 0.372, rescpectively. In S. sobrinus, the median OD were 0.173, 0.012, 0.007 and 0.328. The incorporation of gold nanoparticles into orthodontic adhesives exhibited antibacterial activity against cariogenic microorganism. At a concentration of 0.5 wt% and 1.0 wt% AuNPs, experimental orthodontic adhesive could reduce bacterial growth of both S. mutans and S. sobrinus.
AB - Enamel decalcification usually can be found around orthodontic bracket after debonding. Orthodontic adhesives resistant to bacterial colonization were used to prevent white spot lesion and dental caries in orthodontic treatment with fixed appliance. The objectives of this study were to evaluate the antibacterial properties of expeimental orthodontic adhesive containing gold nanoparticles (AuNPs). 108 orthodontic adhesive discs containing 1.0 wt%, 0.5 wt%, 0.25 wt% AuNPs and without AuNPs were prepared from in-house orthodontic adhesive (27 discs per group). The antibcterial properties of adhesive discs were evaluated by direct contact test. Streptococcus mutans and Streptococcus sobrinus suspensions were placed on the discs and incubated at 37 °C for 1 hour. The adhesive discs were transferred to BHI broth and were incubated at 37◦C for 16, 20 and 24 h. Bacterial growth was evaluated by optical density (OD) measurement at 590nm. The results showed that experimental orthodontic adhesives with 1.0 wt% and 0.5 wt% AuNPs exhibited higher antibacterial activity compared to the control group (p < 0.05). At 24 h of incubation, the median OD of 1.0 wt%, 0.5 wt%, 0.25 wt% and control in S. mutans were 0.109, 0.006, 0.007 and 0.372, rescpectively. In S. sobrinus, the median OD were 0.173, 0.012, 0.007 and 0.328. The incorporation of gold nanoparticles into orthodontic adhesives exhibited antibacterial activity against cariogenic microorganism. At a concentration of 0.5 wt% and 1.0 wt% AuNPs, experimental orthodontic adhesive could reduce bacterial growth of both S. mutans and S. sobrinus.
KW - Antibacterial effect
KW - Gold nanoparticles
KW - Orthodontic adhesives
KW - Streptococcus mutans
KW - Streptococcus sobrinus
UR - http://www.scopus.com/inward/record.url?scp=85122139352&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.904.301
DO - 10.4028/www.scientific.net/KEM.904.301
M3 - Conference contribution
AN - SCOPUS:85122139352
SN - 9783035718775
T3 - Key Engineering Materials
SP - 301
EP - 308
BT - Advanced Materials and Engineering Materials X - Selected peer-reviewed full text papers from the 10th ICAMEM and 7th ICMSSM, 2021
A2 - Wei, Peng Sheng
A2 - Xi, Yan Zhang
PB - Trans Tech Publications Ltd
T2 - 10th International Conference on Advanced Materials and Engineering Materials, ICAMEM 2021 and 7th International Conference on Mechanical Structures and Smart Materials, ICMSSM 2021
Y2 - 14 June 2021 through 15 June 2021
ER -