Abstract
Emblica (Phyllanthus emblica Linn.) has been used to promote the growth of hair in traditional medicine, however less is known regarding its pharmacological activities in hair follicles. To investigate the effects of emblica fruit extracts in terms of hair growth stimulation, the proliferative effects of extract in HaCaT keratinocytes and Dermal Papilla (DP) cells of human hair follicles were determined by MTT assay and cell counts. The results show that emblica extract stimulated proliferation of DP cells in a concentration-dependent manner, whereas it showed minimal effect on keratinocytes, suggesting that the extract might promote hair growth by prolonging the anagen phase through the proliferative effect on DP cells.
| Original language | English |
|---|---|
| Pages (from-to) | 95-100 |
| Number of pages | 6 |
| Journal | Research Journal of Medicinal Plant |
| Volume | 5 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2011 |
| Externally published | Yes |
Keywords
- Dermal papilla cell
- Emblica
- Hair growth
- Keratinocyte
- Phyllanthus emblica Linn