TY - JOUR
T1 - New insights into the biology of the emerging tembusu virus
AU - Hamel, Rodolphe
AU - Phanitchat, Thipruethai
AU - Wichit, Sineewanlaya
AU - Vargas, Ronald Enrique Morales
AU - Jaroenpool, Jiraporn
AU - Diagne, Cheikh Tidiane
AU - Pompon, Julien
AU - Missé, Dorothée
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021
Y1 - 2021
N2 - Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccines and therapeutics, with a particular focus on host–virus interactions.
AB - Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccines and therapeutics, with a particular focus on host–virus interactions.
KW - Emergent arboviruses
KW - Host–pathogen interactions
KW - TMUV
KW - Vector
KW - Zoonosis
UR - http://www.scopus.com/inward/record.url?scp=85113174330&partnerID=8YFLogxK
U2 - 10.3390/pathogens10081010
DO - 10.3390/pathogens10081010
M3 - Review article
AN - SCOPUS:85113174330
SN - 2076-0817
VL - 10
JO - Pathogens
JF - Pathogens
IS - 8
M1 - 1010
ER -
