TY - JOUR
T1 - Transient elastography in end-stage renal disease patients on hemodialysis
T2 - The effect of net fluid withdrawal
AU - Khunpakdee, Narongrit
AU - Jayanama, Kullapong
AU - Kaewdoung, Piyaporn
AU - Promson, Kwannapa
AU - Rattanasiri, Sasivimol
AU - Warodomwichit, Daruneewan
AU - Kantachuvesiri, Surasak
AU - Sobhonslidsuk, Abhasnee
N1 - Publisher Copyright:
© 2015 S. Karger AG, Basel.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Background/Aims: The impact of volume status on liver stiffness measurement (LSM) as measured by transient elastography (TE) as in end-stage renal disease (ESRD) was unclear. We evaluated LSM before and after hemodialysis (HD) and identified the associated factors if the difference of LSM existed. Methods: A cross-sectional study was conducted in ESRD patients on regular HD. Subjects underwent TE and bioelectrical impedance before and after HD. Results: Thirty-six patients were enrolled. Mean (SD) net fluid withdrawal volume (NFWV) per session was 2.55 (0.9) l. Median (range) pre- and post-HD LSMs were 5.38 (2.8-25.7) and 5.4 (2.8-26) kPa, respectively (p = 0.712). Mean differences of pre- and post-HD LSMs correlated with NFWV (r = 0.49, 95% CI 0.19-0.71, p = 0.002). Conclusion: In ESRD on regular HD, LSM is not affected by HD. TE can be done before or after HD with similar results. However, fluid excess at pre-HD can cause inaccurately high LSM.
AB - Background/Aims: The impact of volume status on liver stiffness measurement (LSM) as measured by transient elastography (TE) as in end-stage renal disease (ESRD) was unclear. We evaluated LSM before and after hemodialysis (HD) and identified the associated factors if the difference of LSM existed. Methods: A cross-sectional study was conducted in ESRD patients on regular HD. Subjects underwent TE and bioelectrical impedance before and after HD. Results: Thirty-six patients were enrolled. Mean (SD) net fluid withdrawal volume (NFWV) per session was 2.55 (0.9) l. Median (range) pre- and post-HD LSMs were 5.38 (2.8-25.7) and 5.4 (2.8-26) kPa, respectively (p = 0.712). Mean differences of pre- and post-HD LSMs correlated with NFWV (r = 0.49, 95% CI 0.19-0.71, p = 0.002). Conclusion: In ESRD on regular HD, LSM is not affected by HD. TE can be done before or after HD with similar results. However, fluid excess at pre-HD can cause inaccurately high LSM.
KW - Bioelectrical impedance
KW - End-stage renal disease
KW - Hemodialysis
KW - Liver stiffness measurement
KW - Transient elastography
UR - http://www.scopus.com/inward/record.url?scp=84943339271&partnerID=8YFLogxK
U2 - 10.1159/000439582
DO - 10.1159/000439582
M3 - Article
C2 - 26430774
AN - SCOPUS:84943339271
SN - 0253-5068
VL - 40
SP - 256
EP - 259
JO - Blood Purification
JF - Blood Purification
IS - 3
ER -