Using oral and colon cancer cells for studying the anticancer properties of antimicrobial peptides

Teerakul Arpornsuwan, Wimolpak Sriwai, Hathaitip Sritanaudomchai, Sittiruk Roytrakul

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Antimicrobial peptides (AMPs) are of importance in defense mechanism of many organisms and are potential candidate for treatment of infections in animals and humans. AMPs exhibit a wide range of immunomodulatory activities related to innate immunity, wound healing, and inflammation. AMPs also serve as drug delivery vectors, antitumor agents, and mitogenic agents. Here, we describe the investigation of anticancer and cytotoxic activities of antimicrobial peptides by colorimetric MTT assay using smooth muscle, dental pulp stem cell, human colon cancer cell line (SW620), and human oral squamous carcinoma cell line (HSC4).

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages345-357
Number of pages13
DOIs
Publication statusPublished - 2017

Publication series

NameMethods in Molecular Biology
Volume1548
ISSN (Print)1064-3745

Keywords

  • Antimicrobial peptide
  • Dental pulp stem cell
  • Human colon cancer cell line (SW620)
  • Human oral squamous carcinoma cell line (HSC4)
  • Smooth muscle cell

Fingerprint

Dive into the research topics of 'Using oral and colon cancer cells for studying the anticancer properties of antimicrobial peptides'. Together they form a unique fingerprint.

Cite this