TY - CHAP
T1 - Using oral and colon cancer cells for studying the anticancer properties of antimicrobial peptides
AU - Arpornsuwan, Teerakul
AU - Sriwai, Wimolpak
AU - Sritanaudomchai, Hathaitip
AU - Roytrakul, Sittiruk
N1 - Publisher Copyright:
© Springer Science+Business Media LLC 2017.
PY - 2017
Y1 - 2017
N2 - Antimicrobial peptides (AMPs) are of importance in defense mechanism of many organisms and are potential candidate for treatment of infections in animals and humans. AMPs exhibit a wide range of immunomodulatory activities related to innate immunity, wound healing, and inflammation. AMPs also serve as drug delivery vectors, antitumor agents, and mitogenic agents. Here, we describe the investigation of anticancer and cytotoxic activities of antimicrobial peptides by colorimetric MTT assay using smooth muscle, dental pulp stem cell, human colon cancer cell line (SW620), and human oral squamous carcinoma cell line (HSC4).
AB - Antimicrobial peptides (AMPs) are of importance in defense mechanism of many organisms and are potential candidate for treatment of infections in animals and humans. AMPs exhibit a wide range of immunomodulatory activities related to innate immunity, wound healing, and inflammation. AMPs also serve as drug delivery vectors, antitumor agents, and mitogenic agents. Here, we describe the investigation of anticancer and cytotoxic activities of antimicrobial peptides by colorimetric MTT assay using smooth muscle, dental pulp stem cell, human colon cancer cell line (SW620), and human oral squamous carcinoma cell line (HSC4).
KW - Antimicrobial peptide
KW - Dental pulp stem cell
KW - Human colon cancer cell line (SW620)
KW - Human oral squamous carcinoma cell line (HSC4)
KW - Smooth muscle cell
UR - http://www.scopus.com/inward/record.url?scp=85007486786&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-6737-7_25
DO - 10.1007/978-1-4939-6737-7_25
M3 - Chapter
C2 - 28013517
AN - SCOPUS:85007486786
T3 - Methods in Molecular Biology
SP - 345
EP - 357
BT - Methods in Molecular Biology
PB - Humana Press Inc.
ER -