Utility of a set of conserved mitochondrial cytochrome oxidase subunit I gene primers for Mansonia annulata identification

Chalalai Rueanghiran, Chamnarn Apiwathnasorn, Pradit Sangthong, Yudthana Samung, Jiraporn Ruangsittichai

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)

Abstract

DNA-based identification system using the mitochondrial cytochrome oxidase subunit I (COI) gene has enabled validation of many species in certain taxonomic groups. These primer combinations were able to work universally across Insecta. Here, a set of three primer pairs were successful in amplifying COI of Mansonia annulata mosquito, a potential vector of Brugia malayi. By merging all three amplicons the whole COI was obtained. Primer pair TY-J-1460/C1N2087 amplified 5' region of COI, LepFl/LepRl the central and C1J2090/TL2N3014 the 3' region, generating COI amplicons of 650, 700 and 950 base pairs, respectively. When Ma. annulata sequences were compared with those from online sources, they formed a cluster group that is clearly distinct from other allied species.

Original languageEnglish
Pages (from-to)1381-1387
Number of pages7
JournalSoutheast Asian Journal of Tropical Medicine and Public Health
Volume42
Issue number6
Publication statusPublished - 2011

Keywords

  • COI
  • Mansonia annulata
  • Mitochondrial DNA
  • Primer

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